Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development
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چکیده
منابع مشابه
Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development.
Dorsal spinal cord neurons receive and integrate somatosensory information provided by neurons located in dorsal root ganglia. Here we demonstrate that dorsal spinal neurons require the Krüppel-C(2)H(2) zinc-finger transcription factor Bcl11a for terminal differentiation and morphogenesis. The disrupted differentiation of dorsal spinal neurons observed in Bcl11a mutant mice interferes with thei...
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ژورنال
عنوان ژورنال: Development
سال: 2012
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.072850